Many of you may be wondering: How does Wellmune WGP stimulate the immune system? (If you haven’t read the article that shares clinical proof that it works, you may want to do so first before reading HOW it works.)

First, the science.

Over the last few thousand years of human evolution, your body’s immune system has become very good at killing yeast and fungal infections. These yeasts and fungi attract antibodies that then attract blood proteins called complement. Imagine a round yeast cell with antibodies and complements attached all over its surface. Think of the plugin as flashing signals that say “I may not belong.”

Plugins don’t destroy, they just act as markers for things that may not belong and should be removed. When complements label an invader as alien, neutrophils enter the picture. Neutrophils are the most abundant immune cells in your body and act as the first line of defense. Neutrophils have the ability to kill the invader. But, the plugin only marked it as “May Not Belong” so how does the neutrophil know if it should go ahead with the destruction?

The answer is a second indicator. If both indicators show that the substance is foreign, the neutrophil dispenses with it. What is that second indicator? It is a glycopolysaccharide (also known as beta glucan) found only on the surface of yeast and fungi. So this process works very well against yeasts and fungi, but not against bacteria or viruses, since they do not have the second indicator.

The key is in this fact. For neutrophils to differentiate between normal cells and harmful foreign bodies, they must detect the presence of complements (signal 1) and a Beta Glucan (signal 2). When neutrophils find both, they move on and kill. The neutrophils in your body are always on the lookout for the presence of complement and beta glucans. However, many foreign pathogens do not have beta-glucans (signal 2) on the surface of their cells, so they are ignored by neutrophils.

How does Wellmune WGP fit into this picture as an immune system booster?

Wellmune WGP is classified as beta (1,3)(1,6) glucan, the substance needed to send signal 2. It is a natural product, isolated from a type of baker’s yeast. Wellmune’s job is to provide signal #2 when it’s missing.

It acts as a food for the immune system and an important source of nutrition for the immune system. After digestion, Wellmune WGP is absorbed through the small intestine, where it is broken down into pieces by another type of immune cell known as a macrophage and gradually released over several days.

Neutrophils in your body detect the presence of the released beta-glucans and bind to them, putting them on “partial alert”: signal 2 is given. When the neutrophils go to the site of an infection, they already have the connection to the Beta Glucan ( signal 2), so the neutrophils simply must bind to the complement (signal 1) attached to the foreign intruder to begin killing it. Hence Wellmune’s nickname as an immune system booster.

Wellmune WGP essentially tricks your immune system into thinking bacteria and viruses are yeast or fungus. It takes advantage of the powerful natural response to yeast and fungi to fight bacteria and viruses as well. In doing so, it uses the body’s built-in natural defenses to eliminate bacteria and viruses that the neutrophils would not otherwise have destroyed.

Very smart idea. And it’s clearly working based on the results of animal and human clinical trials to date. Our biggest public health threats are drug-resistant bacteria and new viral infections, not yeasts and fungi. Wellmune WGP gives us a way to have signal 2 “always on” so our neutrophils can be sent against bacteria and viruses, not just yeast and fungi. Stopping an invader early is your best chance of defeating it. Therefore, having a hardened “always on” immune system with an army of readily available neutrophils goes a long way in rapidly suppressing foreign invaders.

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